end stage multiple myeloma treatment

Seek medical care for unexplained pain nausea vomiting weight loss vision problems or chronic tingling or numbness. If it has spread to a different part of the body the stage is regional or distant.

Suggested Approach To The Treatment Of Patients With Newly Diagnosed Download Scientific Diagram

Multiple myeloma is a cancer of the plasma cells in the bone marrow.

. The serum protein value is less than 3 gdL and myeloma-related end-organ damage is absent. As it progresses bone pain anemia kidney dysfunction and infections may occur. The cause of multiple myeloma is unknown.

However there are various factors other than stage that. This disease is the second most common hematologic malignancy after lymphoma and its spectrum of characteristic features are widely known by the acronym CRAB hypercalcemia. Multiple myeloma MM also known as plasma cell myeloma and simply myeloma is a cancer of plasma cells a type of white blood cell that normally produces antibodies.

Often no symptoms are noticed initially. Treatment of multiple myeloma focuses on decreasing the severity of symptoms with medications stem cell transplants bisphosphonate. Plasma cell neoplasms may not respond to treatment or may come back after treatment.

There is no cure for multiple myeloma. Stage II multiple myeloma. Complications may include amyloidosis.

Current research puts the 5-year survival rate for stage III multiple myeloma at about 53. The following stages are used for multiple myeloma. The stage of multiple myeloma is based on the levels of beta-2-microglobulin and albumin in the blood.

Multiple myeloma MM is a clonal plasma cell proliferative disorder characterized by primary infiltration of bone marrow and excessive production of abnormal immunoglobulin. Localized Confined to Primary Site. A variety of cytogenetic.

For myeloma 43 are diagnosed at the local stage. Stage I multiple myeloma. An intermediate disease stage between MGUS and MM termed smoldering MM is characterized by an M protein level of 3 gdL or more and over 10 clonal plasma cells in bone marrow but no symptoms of myeloma-related end-organ damage.

The 5-year relative survival for localized myeloma is 775. Percent of Cases 5-Year Relative Survival by Stage at Diagnosis. Stage III multiple myeloma.

Stage Percent of Cases 5-Year Relative Survival.

Multiple Myeloma Diagnosis And Treatment American Family Physician